Thursday, January 30, 2020

Should School Students Do Part Time Jobs Essay Example for Free

Should School Students Do Part Time Jobs Essay Low Yee Ching 5S1 In my opinion, I agree that school children should be allowed to work after school. Let me explain to you why I think so. Firstly, school children nowadays are very free after school. Therefore, they should be allowed to work after school so that they will not have the chance to get involved in any crime. Besides, they can learn to be independent while working. This is because they always expect everything to be prepared for them. So, it is a good chance for them to learn how to carry out their daily lives without any help. It is very useful to them when they step out into the complicated working society. Furthermore, there are many school children who come from poor families. In the family, their fathers are the only breadwinners. Their pocket money is not enough for them to carry out their daily activities. When their parents experience financial constraints, their pocket money is reduced. Therefore, they take on part-time jobs to earn more pocket money and also to reduce the burden of the family. Moreover, school children can also learn how to manage their time well between studying and working. They should plan a timetable for their studies and do their revision by following the schedule. This is to ensure that they pass their examinations with good results. They are trained to use their time wisely because time is priceless. In addition, school children can obtain more invaluable working experiences while having a part-time job. They meet many new friends and help one another whenever somebody needs a helping hand. Besides this, they also learn how to communicate with the customers. They have the chance to communicate with different personalities and as a result, get to improve their communicative skills. Apart from that, school children can also learn to be more responsible while working. They should finish their work on time and try their best to make it perfect. This can help them to take on their responsibilities more seriously. Moreover, they are given the opportunity to polish their leadership skills. They have to lead the groups to complete their work and also to perform well. In conclusion, I feel that school children should be allowed to work after school as they can learn many things while undertaking a part-time job. We should give them a chance to try because they are the backbones of our country in the future.

Wednesday, January 22, 2020

The Actions of Cocaine in the Brain Essay -- Drugs Addiction Addicted

The Actions of Cocaine in the Brain Cocaine’s mode of action has been shown to involve the dopamine receptors. This paper will discuss how cocaine affects dopamine receptors, the mode of addiction, how cocaine affects the frontal brain metabolic activities, as well as the role of excitatory amino acids in cocaine’s mechanism. I will also discuss how cocaine affects another system through its mechanism on the brain—the renin angiotensin system. Cocaine influences dopamine, norepinephrine and serotonin neurotransmission by inhibiting their reuptake. Pimozide, alpha-flupenthixol, perphenazine and chlorpromazine, all dopamine antagonists, were used to pre-treat rats in an attempt to demonstrate the reinforcing effects of dopamine. Because rats demonstrated a reduced rate of self-administration during extinction as well as after pre-treatment with antagonists, it is conceivable that dopamine receptors are involved in the reinforcing effects of cocaine (Hubner & Moreton, 1991). Two dopamine receptors, B1 and B2, are believed to be involved in these rewarding effects of cocaine. Rats were trained to self-administer cocaine intravenously on a fixed-ratio (FR) 5 schedule of reinforcement. When these rats were pretreated with SCH23390, a D1 antagonist, and spiperone, a D2 antagonist, their response rates varied. At doses up to l0ug/kg, the rats exhibited an increased response rate; whereas at doses higher than this, the rats showed a decrease in their response rate. A similar decrease in response rate was produced when central dopamine containing neurons were destroyed with the neurotoxin, 6-hydroxy-dopamine (Hubner &Moreton, 1991). The mode of action of the D1 receptor subtype is on adenylate cyclase. Upon activation, it s... ... 1. Dackis, C. A., and Gold, M. S. Neurotransmitter and neuroendocrine abnormalities associated with cocaine use. Psychiatric Medicine, 1987, 3: 469-477. 2. Hubner, C. and Moreton, J. Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat. Psychopharmacology, 1991, 105: 151-156. 3. Karler, R. et. al. Excitatory amino acids and the actions of cocaine. Brain Research, 1992, 143-146. 4. Nestler E. Molecular Mechanisms of Drug Addiction. The Journal of Neuroscience, July 1992, 12(7): 2439-2450. 5. Rodriguez-Sanchez, M. et. al. Effect of Prenatal and Postnatal Cocaine Exposure on Somatostatin Content and Binding in Frontoparietal Cortex and Hippocampus of Developing Rat Pups. Peptides, 1991, l2: 951-956. 6.Volkow, N. et al. Long-Term Frontal Brain Metabolic Changes in Cocaine Abusers. Synapse,1997, 11:184-190 The Actions of Cocaine in the Brain Essay -- Drugs Addiction Addicted The Actions of Cocaine in the Brain Cocaine’s mode of action has been shown to involve the dopamine receptors. This paper will discuss how cocaine affects dopamine receptors, the mode of addiction, how cocaine affects the frontal brain metabolic activities, as well as the role of excitatory amino acids in cocaine’s mechanism. I will also discuss how cocaine affects another system through its mechanism on the brain—the renin angiotensin system. Cocaine influences dopamine, norepinephrine and serotonin neurotransmission by inhibiting their reuptake. Pimozide, alpha-flupenthixol, perphenazine and chlorpromazine, all dopamine antagonists, were used to pre-treat rats in an attempt to demonstrate the reinforcing effects of dopamine. Because rats demonstrated a reduced rate of self-administration during extinction as well as after pre-treatment with antagonists, it is conceivable that dopamine receptors are involved in the reinforcing effects of cocaine (Hubner & Moreton, 1991). Two dopamine receptors, B1 and B2, are believed to be involved in these rewarding effects of cocaine. Rats were trained to self-administer cocaine intravenously on a fixed-ratio (FR) 5 schedule of reinforcement. When these rats were pretreated with SCH23390, a D1 antagonist, and spiperone, a D2 antagonist, their response rates varied. At doses up to l0ug/kg, the rats exhibited an increased response rate; whereas at doses higher than this, the rats showed a decrease in their response rate. A similar decrease in response rate was produced when central dopamine containing neurons were destroyed with the neurotoxin, 6-hydroxy-dopamine (Hubner &Moreton, 1991). The mode of action of the D1 receptor subtype is on adenylate cyclase. Upon activation, it s... ... 1. Dackis, C. A., and Gold, M. S. Neurotransmitter and neuroendocrine abnormalities associated with cocaine use. Psychiatric Medicine, 1987, 3: 469-477. 2. Hubner, C. and Moreton, J. Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat. Psychopharmacology, 1991, 105: 151-156. 3. Karler, R. et. al. Excitatory amino acids and the actions of cocaine. Brain Research, 1992, 143-146. 4. Nestler E. Molecular Mechanisms of Drug Addiction. The Journal of Neuroscience, July 1992, 12(7): 2439-2450. 5. Rodriguez-Sanchez, M. et. al. Effect of Prenatal and Postnatal Cocaine Exposure on Somatostatin Content and Binding in Frontoparietal Cortex and Hippocampus of Developing Rat Pups. Peptides, 1991, l2: 951-956. 6.Volkow, N. et al. Long-Term Frontal Brain Metabolic Changes in Cocaine Abusers. Synapse,1997, 11:184-190

Tuesday, January 14, 2020

The First Modern War

Samuel Santiuste Ms. Engelken US History I Honors May 13, 2011 The First Modern War While reading history, we typically see that wars were typically fought with soldiers in close- order formations with a musket that would be fired in unison on command. Everything changed after the American Civil War, a conflict to determine the fate of slaves in the Union, erupted. Today many historians consider the Civil War as the first modern war because it depended on: heavy industry, fast communication and transportation. But this time all of these new technologies were used to its full potential. As a result new weapon technology was mass produced which inflicted heavy losses on both the Union and the Confederate sides and resulted in improved battlefield medicine. Years before the Civil War, soldiers would normally carry muskets that had a fire range of about 250 yards. But although this weapon had an amazing range, the musket only held and fired one bullet at a time and it hit random targets. The accuracy of the musket was from about 80 yards and this caused many of the battles to be fought at a close range. Then, in 1848 the French officer named Claude-Etienne Minie took the design of a bullet that expanded upon fired and â€Å"simplified and improved on earlier designs–including those developed by Britain's Captain John Norton (1818) and William Greener (1836)† to make the bullet that bears its name: the Minie ball (Minie Ball). This new bullet combined with the rifle made a terrific duo because the range of the weapon was from 200-250 yards with a terrific accuracy. To show the bullet’s power alone, during the Crimean War of 1853-56 â€Å"the bullet so improved the effectiveness of infantry troops that 150 soldiers using the Minie ball could equal the firing power of more than 500 with a traditional musket and ammunition† (Minie Ball). When this weapon was introduced to the Civil War, the old model of warfare became obsolete right away because the infantry along with the cavalry could not charge against the enemy as they used to. Other weapons that came into action in the Civil War were not as deadly as the Minie ball but had a big impact on surviving. Despite the fact that the Minie ball was easy to load, soldiers still had to pause in the middle of the action to reload their guns, and this made them easy targets. By 1863, there was a new weapon that solved this problem called repeating rifle because it could fired more than one bullet before the needing of a reload. The most famous type was the Spencer carbine. But like many other technology, this weapon was only available to the Northerners. Many Southerners thought that this weapon was unfair and one Union soldier once wrote: â€Å"they say we are not fair, that we have guns that we load up on Sunday and shoot all the rest of the week† (Civil War Technology). At the end of the war, the statistics showed that the Minie ball combined with the rifle did the most damage because â€Å"with more than 200,000 soldiers killed and more than 400,000 wounded, 90 percent of these causalities were caused by these weapons† (Minie Ball). On the same year that the Civil War started, President Lincoln ordered a blockade on the Confederates to stop their cotton trade and split the confederacy. So to counter attack the Union, many advances in naval warfare were flourishing which led to the built of the H. L. Hunley, which was the first ever effective submarine developed by the Confederates. This Confederate submarine was created to destroy the Union blockade wooden ships with the use of torpedoes that were attached along a long steak that exploded upon contact or by a timer. But before the submarine was ready to attack, it sank three times and on the fourth tried â€Å"it was sent out to attack the U. S. S. Housatonic, and detonated its torpedo, sinking the Housatonic and thereby becoming the first submarine to ever sink an enemy vessel† (Dutch). Despite the best efforts the submarine sank with the blast. Another incredible invention that changed the nature of warfare in the seas was when the ironclad warships came into action. This time both sides had their own version of the ironclad which was powered by a steam engine: Union had the U. S. S. Monitor and the Confederates the C. S. S. Virginia or Merrimack. Once again the Confederates tried to destroy the Union ships using an ironclad â€Å"built upon the charred remains of a burnt wooden warship, clad completely in iron plating down to the waterline and bristling with cannons† (White). This warship just went straight for the blockade in Virginia, and although it was hit by explosives and other heavy artillery the damage was minimal. And this is just a brief view of what might the battle would have been like by Professor J Rickard with the Virginia: On 8 March 1862 she steamed out of Norfolk to attack the Union blockading fleet. Her ten guns were opposed to 219 Union guns on five ships, but the Union ships didn’t stand a chance. First to go was the U. S. S. Cumberland (24 guns), rammed and sunk. The only serious damage inflicted to the Virginia was that her ram broke off and remained stuck in the Cumberland. All of this meant that the Union needed reinforcement, so they sent the Monitor to save the day. These ships battled for â€Å"several hours as their shells and shot bounced off each other's thick armor plating† and the match might have ended in a tie as there were no records telling who won (White). As the iron-clad demonstrated their power, the old wooden ships became obsolete. Even though there was fascinating technology being used in the Civil War, the only two â€Å"weapons† that President Lincoln that used the most were the train and the telegraph. Although the railroads were still a new concept because they were not used much for military purposes, they were still used to attack the enemy and replenish troops. The Union owned about 21,000 miles of railroad tracks while the Confederates only owned about 9,000 miles. Since the beginning of the war both sides used trains to transport ammunition and soldiers to the front lines faster than ever before. Because the trains played a very important role in the war, the enemy used â€Å"rail twisters and devices to blow up railroad bridges and other infrastructure and even some troops specialized in destroying railroad equipment as their sole-role in the war† (AE Aeragon) . Most of the time trains were used for transportation, but on special occasions they were used as rams. Sometimes troops would send trains at full speed to â€Å"damage an enemy train or railroad facilities, or to attack troops and even to destroy bridges† (Koenig). This experienced Confederates soldiers when they saw a train on flames aiming straight for them. Now, the telegraph was located along the railroad tracks and this meant that the North had the upper hand because they have the most railroad miles. The telegraph helped President Lincoln from the White House â€Å"to monitor battlefield reports, lead real-time strategy meetings and deliver orders to his men† (Civil War Technology). This turn out to be a great advantage for the North because they still required the technology and industry to carry out communication tasks. And by 1862 the U. S. Military Telegraph Corps â€Å"trained 1,200 operators, strung 4,000 miles telegraph wire and had sent more than 1,000,000 messages back and for† (Koenig). This alone can tell that during this war that the president was actually involved more than in past wars. Throughout the entire Civil War, diseases were killing more people than weapons because people had little knowledge about the silent killers called germs. Since the beginning of the Civil War in the spring of 1861 â€Å"medically, the United States was woefully prepared and scientists, meanwhile, had yet to come up with the theory that germs cause diseases† (Sohn). This meant that doctors did not know that they should always wash their instruments before operating and the hospital hygiene was very poor which led to disease breakouts. But problems led to many medical advances such as the protocol to treat the injuries. This system was created by Jonathan Letterman, a Union surgeon, who â€Å"created a well-organized system of care that began with triage close to the source of harm and was followed by rapid transportation to a series of clinics, hospitals and specialists† (Sohn). This medical protocol is still essential today. While there medical advancements, many improvements on neurology came about. Physicians began â€Å"the study of phantom limbs, the perception of a missing arm or leg as present and painful† (White). The American physician S. Weir Mitchell discovered phenomenon such as the shell shock and posttraumatic stress syndrome. One of the ways that physicians noticed these problems were when soldiers would freeze or started to shake wildly and many thought it was because that person was a coward. So Mitchell and his colleague, Jacob da Costa, â€Å"came into a conclusion which was that the soldiers were suffering from mental problems, stress and heart diseases† (White). To treat these problems, they said it was necessary the removal and rest from the source causing the stress. The Civil War, an event that could have or could have not being avoided, shaped the future of the entire world. The war had a great impact on anything that ranged from weapons to medicine. It also leaded to the creation of new technology such as the telephone and the improvement on the medical field. Although the war brought many innovations to the United Sates, it is still the bloodiest one in the American history because people from the same nation were being killed and it is similar to what the British Novelists Agatha Christie said about war: One is left with the horrible feeling now that war settles nothing; that to win a war is as disastrous as to lose one. Works Cited â€Å"Civil War Technology. † 2011. The History Channel website. Apr. 27 2011, 11:04 . Dutch, Steven. â€Å"The First Modern War and the Last Ancient War. † University of Wisconsin – Green Bay. N. p. , 02 Jun 2010. Web. 27 Apr 2011. . Koenig, Alan R. â€Å"Railroad's Critical Role in the Civil War. † America's Civil War 1996: n. pag. Web. 27 Apr 2011. . â€Å"Minie Ball. † 2011. The History Channel website. Apr. 27 2011, 11:03 . Rickard, J (1 May 2006), American Civil War: The Blockade and the War at Sea, . Sohn, Emily. â€Å"How the Civil War Changed Modern Medicine. † Discovery News. N. p. , 08 Apr. 2011. Web. 27 Apr 2011. . Stevens, Anthony. Roots of War and Terror. New York: Cromwell Press Ltd, 2044. 212. eBook. â€Å"The US Civil War, the First Modern War. † AE Aeragon. N. p. , n. d. Web. 27 Apr 2011. . White, David. â€Å"Born in the USA: A New World of War. † History Today 60. 6 (2010): 12. Points of View Reference Center. EBSCO. Web. 27 Apr. 2011.

Sunday, January 5, 2020

Stop Burying The Problem Case Study - 990 Words

Title: Stop Burying the Problem: How the County with the Continent’s Most Fertile Lands is Drowning in Waste. From: Mayor of the City of Lviv To: President of Ukraine Preface: In 2017, according to Bloomberg, more than 95% of total Ukrainian solid waste is sent to landfills, with only 4% being sorted for recycling . In the neighboring European Union, those numbers are 45% and 39% respectively . â€Å"If laid out in a continuous blanket† , combined contents of Ukraine’s 6,500 legal and 35,000 illegal dumps could â€Å"cover all of occupied Crimea and the disputed eastern provinces of Luhansk and Donetsk† . As a result, the country that sits on some of the continent’s most fertile lands is drowning in waste. If the dangerous trend continues,†¦show more content†¦Hard to believe that the country that has survived the Chernobyl nuclear accident in 1986 and has witnessed the consequences of this environmental disaster is ready to face yet another similar tragedy by simply having no waste management regulations in place. Summary: There are many root causes to this problem. One of them being the absence of any incentive for Ukrainians to recycle and pay the market price for the collection of trash one produces. Today, Ukrainians pay only the equivalent of 26 cents to 37 cents a month for trash pickup, putting the monthly bill for a family of four in an apartment at just over $1 . Such tariffs are not nearly enough to cover operating costs. With Ukraine being among the poorest countries per capita in Europe, trash collection bills are far lower than economically expedient . Moreover, the calculations behind trash collection bills set by the state do not include, for instance, the situation when the number of people living in an apartment is larger than the number of people registered in that apartment . Businesses are no exception. Trash incineration plants find it difficult to compete with landfills, since the minimum tariff for burial waste in Ukraine is around $6-7 per ton , while in neighboring Poland and Germany the tariffs are $59 and $83 respectivelyShow MoreRelatedBook Report On The Book Club And Don t Waste Utah 1470 Words   |  6 Pagessatisfaction â€Å"through the purchase of more of the fascinating and thrilling range of goods and services being offered† 1. Waste generation was metamorphosing into an economical issue. Unfortunately, as will be discussed, it was still accompanied by health problems. Waste as Livestock Feed One fix for America’s garbage production was to use organic waste as livestock feed, particularly for pigs. As with many solutions, it wasn’t foolproof. According to one source at the time, â€Å"garbage fed hogs [were] notRead MoreCauses of Disasters1071 Words   |  4 Pagesbrought about this impact. Soil and water were also contaminated that resulted to continuous economic problems for countries that are agricultural. In the initial stages, the greatest environmental impact of the tsunami was the damage on ecosystems like coral reefs, coastal areas, plants and animals. These natural features however protected countries from further effects inland. Environmental problems were felt further when buildings and facilities that were used for storage containing chemicals, sewageRead MoreWhy Should I Even Recycle?929 Words   |  4 Pages21st century. As a culture we have industrialized our lives, and with this industrialization we have created a lot of waste. 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The best solution as discussed in this study, and one that has been previously ignored, is taking legal action against all forms of bullying. It will not only stop the bullies but also ensure the victims find justice and that children grow up respecting others. How Parents can Prevent Bulling at School Introduction In recent years, bullying in schoolsRead MoreThe death of a child is the most devastating loss a parent can ever experience. When a parent2200 Words   |  9 Pagesexperience. When a parent losses a child, something in the parents die too. The loss not only destroys the parents’, but also leaves an emptiness that can never be filled. The expectations and hopes of a future together are all just a dream now. Burying your child defies the natural order of life events: parents are not supposed to bury their children, children are supposed to bury their parents. Their life is forever changed and will never be the same. The parent not only mourns the loss of theRead MoreThe Difficulty Of Treating Illnesses2227 Words   |  9 PagesAnother example of the difficulty of treating illnesses in Africa is malaria. The study at hand examines locals’ conceptions about health care. The questionnaire was distributed to households in Ethiopia and asked questions concerning their knowle dge of malaria and their preferred forms of treatment (Deressa et al. 2008). The results showed that the respondents’ knew a relatively high amount of information about malaria and how it is contracted; however, this knowledge did not largely influence local’sRead MoreCase Study: Scope Management3492 Words   |  14 PagesResearch in Brief: IT Project Failure – Burying Our Heads in the Sand 5.5   CONTROL SYSTEMS   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Configuration Management 5.6   PROJECT CLOSEOUT Summary Key Terms Discussion Questions Problems Case Study 5.1: Calcutta’s Metro Case Study 5.2: Project Management at Dotcom.com Cas Study 5.3: Runaway Scope – The Bradley FightingRead MoreThe Chernobyl Nuclear Accident Occurred2826 Words   |  12 Pages26, 1986 in the Ukrainian SSR, which was still under the jurisdiction of the Soviet Union at that time. Now, this place pertains to Ukraine, which is an independent country in Eastern Europe. This technological disaster created many health-related problems and affected economically the Eastern European population in the following years after the accident. On Saturday, April 26, one of the reactors at the Chernobyl nuclear plant became very unstable as a routine shutdown was taking place. This was not